SCHEMBL1415906

SCHEMBL1415906

O=C(O)Cc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.73
AKR1B1 P15121 1/20 0.67
LMNA P02545 2/20 0.63
ABCC4 O15439 1/20 0.63
GAA P10253 1/20 0.63
TSHR P16473 1/20 0.63
PTGS1 P23219 1/20 0.63
HTT P42858 1/20 0.63
ALDH1A1 P00352 1/20 0.61
FFAR1 O14842 1/20 0.57
CA2 P00918 1/20 0.56
CAMK2A Q9UQM7 1/20 0.56
NR1H4 Q96RI1 1/20 0.53
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KMT2A Q03164 2/20 0.50
NSD2 O96028 1/20 0.50
POLB P06746 1/20 0.50
GRK2 P25098 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL11705397 0.98 SRD5A2 (0.71) SRD5A2AKR1B1LMNAABCC4GAA
SCHEMBL16091058 0.94 LMNA (0.74) SRD5A2AKR1B1LMNAABCC4GAA
Benzophenone SCHEMBL8820654 0.93 AKR1B1 (0.77) SRD5A2AKR1B1LMNAABCC4GAA
SCHEMBL3468559 0.85 CA2 (0.79) SRD5A2AKR1B1LMNAABCC4GAA
SCHEMBL29163965 0.85 SRD5A2 (0.79) SRD5A2GAAHTTALDH1A1ATM
SCHEMBL6238323 0.85 ALDH1A1 (0.73) SRD5A2GAAHTTALDH1A1FFAR1
SCHEMBL11135171 0.83 SRD5A2 (0.59) SRD5A2AKR1B1LMNAABCC4GAA
SCHEMBL11054849 0.83 ALDH1A1 (0.56) SRD5A2LMNAHTTALDH1A1ATM
SCHEMBL8719473 0.83 ALDH1A1 (0.56) SRD5A2LMNAHTTALDH1A1ATM
SCHEMBL7936989 0.83 ALDH1A1 (0.56) SRD5A2LMNAALDH1A1CA2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802765-B2 Aqueous copolymer dispersion and coating composition ROHM AND HAAS COMPANY (US) 2014-08-12 US claimed
EP-2371913-B1 Aqueous copolymer dispersion and coating composition ROHM & HAAS (US) 2013-03-20 EP claimed
US-20110245390-A1 AQUEOUS COPOLYMER DISPERSION AND COATING COMPOSITION ROHM AND HAAS COMPANY 2011-10-06 US claimed
EP-2371913-A1 Aqueous copolymer dispersion and coating composition Rohm and Haas Company (US) 2011-10-05 EP claimed
EP-4709801-A1 ARCHITECTURAL COATING COMPOSITION Rohm and Haas Company (US) 2026-03-18 EP disclosed
WO-2024233076-A1 ARCHITECTURAL COATING COMPOSITION ROHM AND HAAS COMPANY (US) 2024-11-14 WO disclosed
US-11891519-B2 Asphalt composition and method of using same in tack coats BASF SE (DE) 2024-02-06 US disclosed
CN-113939568-B Aqueous dispersion and aqueous coating composition 陶氏环球技术有限责任公司 2023-12-22 CN disclosed
EP-3775049-B1 ASPHALT COMPOSITION AND METHOD OF USING SAME IN TACK COATS BASF SE (DE) 2023-10-18 EP disclosed
US-20220235215-A1 AQUEOUS DISPERSION AND AQUEOUS COATING COMPOSITION COMPRISING THE SAME DOW SILICONES CORPORATION 2022-07-28 US disclosed
EP-3994224-A1 AQUEOUS DISPERSION AND AQUEOUS COATING COMPOSITION COMPRISING THE SAME Dow Global Technologies, LLC (US) 2022-05-11 EP disclosed
CN-113939568-A Aqueous dispersion and aqueous coating composition 陶氏环球技术有限责任公司 2022-01-14 CN disclosed
EP-1046682-A1 Aqueous pigmented coating agents BASF AKTIENGESELLSCHAFT (DE) 2000-10-25 EP disclosed
US-6060532-A LOW TEMPERATURE FLEXIBILITY AND DIRT PICK UP AND LOW TACK; USEFUL FOR MASTIC COATINGS, CAULKS, AND SEALANTS ROHM AND HAAS COMPANY (US) 2000-05-09 US disclosed
EP-0970993-A1 Aqueous composition BASF AKTIENGESELLSCHAFT (DE) 2000-01-12 EP disclosed
EP-0522789-A2 Multi-staged binder for use in elastomeric coatings, mastic coatings, caulks and sealants ROHM AND HAAS COMPANY (US) 1993-01-13 EP disclosed
EP-0169512-B1 NOVEL TYLOSIN DERIVATIVES Sanraku Incorporated (JP) 1988-09-28 EP disclosed
CN-86105309-A Oxindole-3-carbonyl amines the compound that replaces as the 1-of anti-inflammatory and anodyne 1987-01-14 CN disclosed
US-4612372-A Tylosin derivatives SANRAKU INCORPORATED (JP) 1986-09-16 US disclosed
EP-0169512-A1 Novel tylosin derivatives Sanraku Incorporated (JP) 1986-01-29 EP disclosed