Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177074 | 0.90 | GAA (0.57) | ALDH1A1KDM4ECYP1A2CYP2C19DHODH | |
| SCHEMBL5177067 | 0.90 | GAA (0.57) | ALDH1A1KDM4ECYP1A2CYP2C19DHODH | |
| SCHEMBL5691805 | 0.85 | CA1 (0.52) | — | |
| SCHEMBL5691802 | 0.85 | CA1 (0.52) | — | |
| SCHEMBL5177147 | 0.84 | PARP1 (0.57) | ALDH1A1KDM4ENPC1RAB9APARP1 | |
| SCHEMBL5177143 | 0.84 | PARP1 (0.57) | ALDH1A1KDM4ENPC1RAB9APARP1 | |
| SCHEMBL7934347 | 0.81 | PARP1 (0.50) | ALDH1A1KDM4ENPC1RAB9APARP1 | |
| SCHEMBL7932745 | 0.79 | PARP1 (0.64) | ALDH1A1CYP1A2RAB9APARP1SMN1; SMN2 | |
| SCHEMBL5174592 | 0.75 | KDM4E (0.56) | ALDH1A1KDM4ENPC1RAB9APARP1 | |
| SCHEMBL5177083 | 0.74 | GAA (0.58) | ALDH1A1KDM4ECYP1A2CYP2C19DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174989-B1 | SYNTHETIC RUBBERS AND VULCANIZATION FOR TIRES | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-01-16 | — | — | US | disclosed |
| US-5981662-A | VULCANIZATES FOR USE IN SIDEWALL, TREAD, CARCASS PLY, WIRECOAT OR OVERLAY COMPOUNDS FOR TIRES; IMPART ANTI-REVERSION AND ANTIFATIGUE PROPERTIES IN THE RUBBER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0908489-A2 | Rubber compounds containing polymeric bis-succinimide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |