Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5174592 | 0.93 | KDM4E (0.56) | PARP1NPC1SMN1; SMN2RAB9ADDAH1 | |
| SCHEMBL5177147 | 0.91 | PARP1 (0.57) | PARP1NPC1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL5177143 | 0.91 | PARP1 (0.57) | PARP1NPC1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL7932745 | 0.85 | PARP1 (0.64) | PARP1SMN1; SMN2RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL7937038 | 0.81 | ALDH1A1 (0.48) | PARP1NPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL26659359 | 0.76 | MAPT (0.55) | PARP1NPC1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL26659387 | 0.76 | MAPT (0.55) | PARP1NPC1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL5177074 | 0.75 | GAA (0.57) | PARP1NPC1RAB9ATSHRNFKB1 | |
| SCHEMBL5177067 | 0.75 | GAA (0.57) | PARP1NPC1RAB9ATSHRNFKB1 | |
| SCHEMBL5459512 | 0.74 | PARP1 (0.65) | PARP1NPC1SMN1; SMN2RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174989-B1 | SYNTHETIC RUBBERS AND VULCANIZATION FOR TIRES | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-01-16 | — | — | US | disclosed |
| US-5981662-A | VULCANIZATES FOR USE IN SIDEWALL, TREAD, CARCASS PLY, WIRECOAT OR OVERLAY COMPOUNDS FOR TIRES; IMPART ANTI-REVERSION AND ANTIFATIGUE PROPERTIES IN THE RUBBER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0908489-A2 | Rubber compounds containing polymeric bis-succinimide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |