SCHEMBL5174592

SCHEMBL5174592

C/C(=C\C(N)=O)C(=O)Nc1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.56
▸ DDAH1 O94760 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.53
▸ NPC1 O15118 4/20 0.51
▸ RAB9A P51151 4/20 0.51
▸ KIF11 P52732 1/20 0.51
▸ MAPT P10636 2/20 0.47
▸ TGM2 P21980 1/20 0.47
▸ POLB P06746 2/20 0.47
▸ PARP1 P09874 1/20 0.46
▸ ALDH1A1 P00352 2/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ NMT1 P30419 1/20 0.45
▸ PKM P14618 1/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934347 0.93 PARP1 (0.50) KDM4EDDAH1TDP1NPC1RAB9A
SCHEMBL5177143 0.84 PARP1 (0.57) KDM4ENPC1RAB9AMAPTTGM2
SCHEMBL5177147 0.84 PARP1 (0.57) KDM4ENPC1RAB9AMAPTTGM2
SCHEMBL28716771 0.82 TDP1 (0.61) KDM4EDDAH1TDP1NPC1RAB9A
SCHEMBL7932745 0.79 PARP1 (0.64) TDP1RAB9APOLBPARP1ALDH1A1
SCHEMBL12853847 0.79 TDP1 (0.57) KDM4EDDAH1TDP1NPC1RAB9A
SCHEMBL12597618 0.77 KDM4E (0.68) KDM4EDDAH1TDP1NPC1RAB9A
SCHEMBL6850999 0.77 KDM4E (0.79) KDM4ETDP1NPC1RAB9AKIF11
SCHEMBL25668512 0.75 TDP1 (0.68) KDM4ETDP1NPC1RAB9AKIF11
SCHEMBL23918242 0.75 DDAH1 (0.64) KDM4EDDAH1TDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 — — EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 — — EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 — — EP disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 — — EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 — — US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 — — EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 — — US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 — — EP disclosed
US-20040086799-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-05-06 — — US disclosed
US-6680161-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-01-20 — — US disclosed
EP-1371500-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-12-17 — — EP disclosed
US-20030190553-A1 Support with hydrophilic surface; multilayer; latex layer and ink receiver FUJIFILM CORPORATION (JP) 2003-10-09 — — US disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 — — US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 — — US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 — — US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 — — EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 — — EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 — — EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 — — EP disclosed
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