Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.75 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.72 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | MC4R | P32245 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | MC3R | P41968 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149115 | 1.00 | ADRB2 (0.75) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL7149113 | 1.00 | ADRB2 (0.75) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL9468004 | 0.94 | ADRB1 (0.69) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL7151266 | 0.92 | ADRB1 (0.80) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL9468422 | 0.92 | ADRB1 (0.80) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL7151262 | 0.92 | ADRB1 (0.80) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL7150598 | 0.91 | ADRB1 (0.69) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL11174787 | 0.91 | ADRB1 (0.69) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL7150596 | 0.91 | ADRB1 (0.69) | ADRB2ADRB1ADRB3CYP3A4MAPK1 | |
| SCHEMBL7149121 | 0.91 | ADRB1 (0.69) | ADRB2ADRB1ADRB3CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248573-B1 | SULFONYLATING OR HALOGENATING A (S)-1-PHENYL-2-PROPANOL DERIVATIVE TO PRODUCE (S)-1-PHENYL-2-SUBSTITUTED PROPANE DERIVATIVE; CHEMICAL INTERMEDIATE FOR SYNTHESIS OF ANTIOBESITY DRUG | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5902900-A | OPTICAL PURITY, USE AS ANTI-OBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| US-5679557-A | Process of asymmetrically reducing 1-phenyl-2-oxo-propane derivatives with microorganisms | DAICEL CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0627397-B1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEM (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5508461-A | ANTIOBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0627397-A1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4490392-A | Benzylalcohol derivative and process for preparing | TANABE SEIYAKU CO., LTD. (JP) | 1984-12-25 | — | — | US | disclosed |