SCHEMBL7937157

SCHEMBL7937157

c1ccc(C2CCCC2(c2ccccc2)C2CCCC2)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.41
MAOA P21397 6/20 0.41
MAOB P27338 6/20 0.41
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
SLC6A9 P48067 2/20 0.36
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160266 0.95 SLC6A2 (0.42) KDM1AMAOAMAOBSLC6A2SLC6A4
SCHEMBL2368918 0.95 SLC6A2 (0.42) KDM1AMAOAMAOBSLC6A2SLC6A4
SCHEMBL19192967 0.78 MEN1 (0.44) KDM1AMAOAMAOBSLC6A2SLC6A4
SCHEMBL27826925 0.74 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3
SCHEMBL9295240 0.73 KDM1A (0.44) KDM1AMAOAMAOBSLC6A2SLC6A4
SCHEMBL9004263 0.72 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3
SCHEMBL1582587 0.71 KDM1A (0.43) KDM1AMAOAMAOBTRPA1
SCHEMBL8992430 0.71 KDM1A (0.61) KDM1AMAOAMAOB
SCHEMBL28223342 0.71 TRPA1 (0.45) KDM1AMAOAMAOBSLC6A9TRPA1
SCHEMBL31143852 0.71 KDM1A (0.43) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112308-A1 FIRE RESISTANT STYRENE POLYMER FOAMS WITH REDUCED BROMINATED FIRE RETARDANT THE DOW CHEMICAL COMPANY (US) 2001-07-04 EP disclosed
WO-2000012593-A1 FIRE RESISTANT STYRENE POLYMER FOAMS WITH REDUCED BROMINATED FIRE RETARDANT THE DOW CHEMICAL COMPANY (US) 2000-03-09 WO disclosed