Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943214 | 0.98 | CYP3A4 (0.42) | CYP3A4SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL25891609 | 0.83 | MCL1 (0.40) | CYP3A4SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11228437 | 0.80 | HSD17B10 (0.42) | CYP3A4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7170546 | 0.80 | ALDH1A1 (0.37) | SMN1; SMN2NPC1HTTMAPTALDH1A1 | |
| SCHEMBL11672590 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2NPC1HTTMAPTALDH1A1 | |
| SCHEMBL7943210 | 0.78 | CYP3A4 (0.42) | CYP3A4SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL7943204 | 0.78 | TAS1R3 (0.36) | CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL26204831 | 0.77 | TSHR (0.48) | CYP3A4SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10605055 | 0.77 | RXRB (0.30) | — | |
| SCHEMBL20940106 | 0.75 | HPGD (0.40) | SMN1; SMN2NPC1RAB9AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571405-B1 | Process for preparing 4-alkylsulfonyl-1-alkyl-2-chlorobenzenes and intermediates | HOECHST AG (DE) | 1996-05-01 | — | — | EP | claimed |
| EP-0571405-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE. | HOECHST AG (DE) | 1993-12-01 | — | — | EP | claimed |
| WO-1992014700-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-03 | — | — | WO | claimed |
| JP-8176097-A | — | — | None | — | — | JP | disclosed |
| US-6258984-B1 | CHLORINATION OF P-ALKYLBENZENESULFONYL CHLORIDE | CLARIANT GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-0619303-B1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| JP-H08176097-A | PRODUCTION OF 4-METHYLSULFONYL-1-METHYL-2-CHLOROBENZENE | HOECHST AG | 1996-07-09 | — | — | JP | disclosed |
| EP-0571405-B1 | Process for preparing 4-alkylsulfonyl-1-alkyl-2-chlorobenzenes and intermediates | HOECHST AG (DE) | 1996-05-01 | — | — | EP | disclosed |
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0619303-A1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |
| EP-0571405-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE. | HOECHST AG (DE) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992014700-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-03 | — | — | WO | disclosed |
| US-4882001-A | CAMPHOR QUINONE, ARYL SULFINATE, THICKENERS AND ADHESION PROMOTERS AND OR ACCELERATORS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-11-21 | — | — | US | disclosed |
| US-4349454-A | ENCAPSULATION OF A HYDROPHOBIC-SOLVENT SOLUTION OF A DIAMINODIARYL METHANE SULFONE DERIVATIVE | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1982-09-14 | — | — | US | disclosed |