SCHEMBL7937285

SCHEMBL7937285

O=C(c1ccc(F)cc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.70
CES2 O00748 2/20 0.61
CES1 P23141 2/20 0.61
LTA4H P09960 1/20 0.61
VNN1 O95497 1/20 0.59
CYP1A1 P04798 2/20 0.59
CYP1B1 Q16678 2/20 0.59
EPHX2 P34913 1/20 0.54
PAX8 Q06710 1/20 0.53
GSK3B P49841 2/20 0.52
PTPN1 P18031 1/20 0.52
ESR1 P03372 2/20 0.51
HSD11B1 P28845 1/20 0.50
CYP2C8 P10632 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648641 0.91 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2GSK3B
Hydrochloric Acid SCHEMBL27733522 0.89 SRD5A2 (0.79) SRD5A2CES2CES1EPHX2GSK3B
SCHEMBL20010796 0.87 CES2 (0.83) SRD5A2CES2CES1VNN1CYP1A1
SCHEMBL5980475 0.86 CES2 (0.55) SRD5A2CES2CES1LTA4HVNN1
SCHEMBL13410662 0.84 SRD5A2 (0.73) SRD5A2CES2CES1EPHX2GSK3B
SCHEMBL28000964 0.84 SRD5A2 (0.73) SRD5A2CES2CES1EPHX2GSK3B
SCHEMBL10033819 0.83 LTA4H (0.52) SRD5A2CES2CES1LTA4HVNN1
SCHEMBL238259 0.83 LTA4H (0.73) SRD5A2CES2CES1LTA4HPTPN1
SCHEMBL7716519 0.83 LTA4H (0.52) SRD5A2CES2CES1LTA4HVNN1
SCHEMBL1736339 0.83 LTA4H (0.73) SRD5A2CES2CES1LTA4HPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037164-A Polyaryletherketone sequence copolymer, preparation method thereof and application thereof in 3D printing 吉林大学 2026-05-15 CN claimed
CN-122037164-A Polyaryletherketone sequence copolymer, preparation method thereof and application thereof in 3D printing 吉林大学 2026-05-15 CN disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
US-4454350-A Process for the acylation of halo- or trihalomethylbenzenes RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1984-06-12 US disclosed
US-4453012-A REACTION OF A HALO OR TRIHALOMETHYL BENZENE WITH A TRIHALOMETHYLATED ALIPHATIC OR AROMATIC COMPOUND RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-06-05 US disclosed
US-4446078-A REACTING A POLYHALOALKOXY- OR POLYHALOALKYLTHIOBENZENE WITH A CARBOXYLIC DERIVATIVE, BORON TRIFLUORIDE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-05-01 US disclosed