Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7105573 | 0.81 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL4632824 | 0.80 | RET (0.39) | HTR2AHTR6SIGMAR1RETMEN1 | |
| SCHEMBL3381692 | 0.79 | BRD4 (0.36) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL4469581 | 0.79 | HTR2A (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL4632870 | 0.79 | RET (0.36) | HTR2AHTR6SIGMAR1OPRK1RET | |
| SCHEMBL9226208 | 0.78 | SIGMAR1 (0.35) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL7752430 | 0.78 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL7752433 | 0.77 | HTR2A (0.35) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL4457209 | 0.76 | BRD4 (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL7108175 | 0.76 | HTR6 (0.32) | HTR2AHTR6SIGMAR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232414-B1 | USING ORGANOMETALLIC COORDINATION CATALYST | PHILLIPS PETROLEUM COMPANY | 2001-05-15 | — | — | US | disclosed |