Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938509 | 0.77 | ESR1 (0.39) | LMNACYP3A4HSD17B10ALOX15CA1 | |
| SCHEMBL18338 | 0.76 | CA1 (0.50) | LMNACYP3A4HSD17B10ALOX15CA1 | |
| SCHEMBL7935649 | 0.76 | CA1 (0.31) | CA1CA2CA9ACHE | |
| SCHEMBL7940657 | 0.76 | ESR1 (0.39) | LMNACYP3A4HSD17B10ALOX15CA1 | |
| SCHEMBL11057261 | 0.76 | ESR1 (0.42) | LMNACYP3A4HSD17B10ALOX15CA1 | |
| SCHEMBL11022392 | 0.74 | ALOX15 (0.47) | LMNACYP3A4HSD17B10ALOX15CA1 | |
| SCHEMBL7935399 | 0.71 | MAPK1 (0.46) | LMNACYP3A4HSD17B10ALOX15CA1 | |
| SCHEMBL7937242 | 0.71 | MEN1 (0.37) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL28145577 | 0.70 | ESR1 (0.58) | LMNACYP3A4HSD17B10ALOX15CA1 | |
| SCHEMBL11240213 | 0.70 | ESR1 (0.42) | LMNACYP3A4HSD17B10ALOX15TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| CN-1263882-A | Method for preparing fluorine-substituted aromatic compound | MITSUI CHEMICALS INC (JP) | 2000-08-23 | — | — | CN | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |