SCHEMBL7940657

SCHEMBL7940657

[O-][S+](c1ccc(O)cc1)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.39
ESR2 Q92731 8/20 0.39
LMNA P02545 3/20 0.38
CYP3A4 P08684 3/20 0.38
HSD17B10 Q99714 3/20 0.38
ALOX15 P16050 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
TYR P14679 2/20 0.38
HPGD P15428 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CA3 P07451 2/20 0.38
HIF1A Q16665 2/20 0.38
CA14 Q9ULX7 2/20 0.38
CA12 O43570 2/20 0.38
CA9 Q16790 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
GMNN O75496 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL10432095 0.85 CA12 (0.46) ESR1ESR2CYP3A4CA1CA2
SCHEMBL7929166 0.78 CA1 (0.32) CA1CA2CA9ACHE
SCHEMBL11057261 0.76 ESR1 (0.42) ESR1ESR2LMNACYP3A4HSD17B10
SCHEMBL15391669 0.76 MEN1 (0.38) LMNACYP3A4HSD17B10ALOX15CA1
SCHEMBL7937342 0.76 LMNA (0.38) ESR1ESR2LMNACYP3A4HSD17B10
SCHEMBL7052956 0.76
SCHEMBL7651489 0.76 LMNA (0.38) LMNACYP3A4CA1CA2HPGD
SCHEMBL6760551 0.76 ACHE (0.38) HSD17B10CA1CA2ALDH1A1CA3
SCHEMBL17288700 0.76
SCHEMBL789123 0.76 CYP2A6 (0.38) ALOX15CA1CA2ALDH1A1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415311-B Process for preparing organic sulfones 巴斯夫欧洲公司 2021-07-23 CN disclosed
EP-2938601-B1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2018-05-16 EP disclosed
EP-2938601-B1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2018-05-16 EP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9920004-B2 Method for producing phenolic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-20 US disclosed
US-9920004-B2 Method for producing phenolic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-20 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-20170137377-A1 METHOD FOR PRODUCING PHENOLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 US disclosed
US-20170137377-A1 METHOD FOR PRODUCING PHENOLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 US disclosed
US-9615580-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-11 US disclosed
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-05 US disclosed
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-05 US disclosed
EP-2938601-A1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Company Limited (JP) 2015-11-04 EP disclosed
WO-2014104407-A1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 WO disclosed
WO-2014104407-A1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
CN-1263882-A Method for preparing fluorine-substituted aromatic compound MITSUI CHEMICALS INC (JP) 2000-08-23 CN disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0070443-A1 Thionophosphonic acid esters, process for preparing them and their use as pesticides BAYER AG (DE) 1983-01-26 EP disclosed
US-4164575-A Combating pests with O-alkyl-O-trifluoromethylsulphinylphenyl-thiono(thiol)-phosphoric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1979-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137377-A1 METHOD FOR PRODUCING PHENOLIC COMPOUND HAO2, AOX1, QSOX1 ESR1 2437/4885ESR2 1276/4885LMNA 4064/4885
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL AFF1, AFF2, PYM1 ESR1 2504/4885ESR2 2308/4885LMNA 1384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.