Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 3/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164377 | 0.81 | YTHDC1 (0.41) | SLC29A1CYP1A2YTHDC1IDH2CCNE2 | |
| SCHEMBL30560025 | 0.81 | YTHDC1 (0.41) | SLC29A1CYP1A2YTHDC1IDH2CCNE2 | |
| SCHEMBL20164620 | 0.77 | SLC29A1 (0.40) | SLC29A1CDK1 | |
| SCHEMBL20164352 | 0.73 | HTT (0.40) | SLC29A1KDM4E | |
| SCHEMBL20164505 | 0.71 | SLC29A1 (0.41) | SLC29A1ESR1 | |
| SCHEMBL20164488 | 0.71 | SLC29A1 (0.41) | SLC29A1ESR1 | |
| SCHEMBL20164537 | 0.71 | SLC29A1 (0.41) | SLC29A1ESR1 | |
| SCHEMBL1692066 | 0.69 | IDH2 (0.50) | ALDH1A1IDH2CCNE2CCNE1CDK2 | |
| SCHEMBL20164425 | 0.68 | YTHDC1 (0.38) | SLC29A1CDK1YTHDC1 | |
| SCHEMBL20164616 | 0.68 | SLC29A1 (0.46) | SLC29A1KDM4EALDH1A1IDH2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |