SCHEMBL7938010

SCHEMBL7938010

CC(=O)OCOC(=O)C1CC(C)(C)N([O])C(C)(C)C1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8051064 0.87 ALDH1A1 (0.36) MAOBCYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL8050332 0.85 CYP2C19 (0.32) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL8052210 0.84
SCHEMBL8039672 0.83 ALDH1A1 (0.33) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL1813544 0.81 CYP3A4 (0.44) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL3051796 0.81
SCHEMBL1814694 0.74 BRD4 (0.39)
SCHEMBL8049998 0.74 NAAA (0.36) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL27752052 0.74 ALDH1A1 (0.39)
SCHEMBL31217646 0.73 ALDH1A1 (0.33) CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6239145-B1 USABLE IN ACQUIRING INFORMATION ABOUT ACTIVE OXYGEN OR IN VIVO FREE RADICALS AS BIOLOGICAL IMAGES SUCH AS MAGNETIC RESONANCE IMAGES OR MAGNETOENCEPHALOGRAMS; DAIITCHI RADIOISOTOPE LABORATORIES, LTD. (JP) 2001-05-29 US disclosed
EP-0995740-A1 NOVEL NITROXYL COMPOUNDS AND DRUGS AND REAGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) 2000-04-26 EP disclosed