Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5176426 | 0.88 | TSHR (0.48) | TSHRALDH1A1NPC1MAPTHPGD | |
| SCHEMBL3158793 | 0.85 | TSHR (0.50) | TSHRNPC1MAPTMAPK1RAB9A | |
| SCHEMBL29375733 | 0.83 | SOS1 (0.56) | SOS1HSPB1SCN4ATSHRALDH1A1 | |
| SCHEMBL6289867 | 0.80 | SOS1 (0.58) | SOS1HSPB1SCN4ATSHRALDH1A1 | |
| SCHEMBL6290683 | 0.80 | SOS1 (0.58) | SOS1HSPB1SCN4ATSHRALDH1A1 | |
| SCHEMBL351854 | 0.80 | SOS1 (0.58) | SOS1HSPB1SCN4ATSHRALDH1A1 | |
| SCHEMBL7542333 | 0.79 | TSHR (0.59) | SOS1TSHRNPC1RAB9ALTA4H | |
| SCHEMBL7938383 | 0.79 | LTA4H (0.46) | SOS1HSPB1RAB9ALTA4HMAPK14 | |
| SCHEMBL7938045 | 0.78 | TSHR (0.43) | TSHRNPC1RAB9ACYP3A4KCNN4 | |
| SCHEMBL28834561 | 0.78 | KMT2A (0.58) | HSPB1TSHRALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |