SCHEMBL351854

SCHEMBL351854

Fc1ccc(Oc2ccc(F)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.58
HSPB1 P04792 1/20 0.58
SCN4A P35499 2/20 0.50
GAA P10253 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
LTA4H P09960 3/20 0.47
KDM4E B2RXH2 1/20 0.46
NFE2L2 Q16236 1/20 0.44
EPHX2 P34913 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290683 1.00 SOS1 (0.58) SOS1HSPB1SCN4AGAAMEN1
SCHEMBL6289867 1.00 SOS1 (0.58) SOS1HSPB1SCN4AGAAMEN1
SCHEMBL7367702 0.97 SOS1 (0.56) SOS1HSPB1SCN4AGAAMEN1
SCHEMBL31655464 0.91 SOS1 (0.52) SOS1HSPB1SCN4AGAAMEN1
SCHEMBL255272 0.88 LTA4H (0.67) SOS1HSPB1MEN1KMT2ATSHR
Phosphine SCHEMBL23466364 0.86 LTA4H (0.63) SOS1HSPB1MEN1KMT2ATSHR
SCHEMBL5175480 0.86 NFE2L2 (0.64) SOS1HSPB1MEN1KMT2AALDH1A1
SCHEMBL805908 0.86 MAPT (0.58) SOS1HSPB1SCN4AGAAMEN1
Ammonia Solution, Strong SCHEMBL4263312 0.86 LTA4H (0.63) SOS1HSPB1MEN1KMT2ATSHR
SCHEMBL5175115 0.86 MAOA (0.58) SOS1HSPB1SCN4AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059903-A Trifluoromethyl-containing fluorinated phenyl ether derivative, and preparation method and application thereof 江西凯信生物医药有限公司 2026-05-19 CN claimed
CN-120192679-A Ink, film, light-emitting device and display device 广东聚华印刷显示技术有限公司 2025-06-24 CN claimed
CN-119390953-B Method for preparing polyether ketone and product obtained by same 汕头大学 2025-04-04 CN claimed
CN-119390953-A Method for preparing polyether ketone and product obtained by same 汕头大学 2025-02-07 CN claimed
WO-2024221958-A1 PREPARATION METHOD FOR MODIFIED POLYETHERSULFONE/POLYETHERIMIDE POLYMER ALLOY 深圳先进技术研究院 2024-10-31 WO claimed
CN-118367211-A Sodium ion battery electrolyte capable of inhibiting growth of sodium dendrite 西北师范大学 2024-07-19 CN claimed
CN-117497858-A Electrolyte and lithium ion battery 蜂巢能源科技股份有限公司 2024-02-02 CN claimed
CN-116675861-A Preparation method of modified polyethersulfone/polyetherimide polymer alloy 深圳先进技术研究院 2023-09-01 CN claimed
CN-113429532-B Application of polyether-ether-ketone prepared from 1-butyl-3-methylimidazole bromide in selective laser sintering 江汉大学 2023-05-23 CN claimed
CN-113321800-B Application of selective laser sintering by taking polyether-ether-ketone prepared from tetramethyl guanidine tetrafluoroborate as raw material 江汉大学 2023-05-23 CN claimed
CN-107964079-A A kind of preparation method of polyether-ether-ketone 江汉大学 2018-04-27 CN claimed
US-8029850-B2 Method of manufacturing organic electroluminescent device and method of manufacturing device SEIKO EPSON CORPORATION (JP) 2011-10-04 US claimed
US-6541647-B2 Active materials; drugs; antiinflammatory agents; antiallergens MILLENNIUM PHARMACEUTICALS, INC. 2003-04-01 US claimed
US-20020035278-A1 Methods for synthesis of substituted tetrahydrofuran compound MILLENNIUM PHARMACEUTICALS, INC. 2002-03-21 US claimed
CN-1070880-C Method for preparing polyarylene sulfide with high molecular and high toughness UNIV SICHUAN UNITED (CN) 2001-09-12 CN claimed
EP-1102759-A1 METHODS FOR SYNTHESIS OF SUBSTITUTED TETRAHYDROFURAN COMPOUND Millennium Pharmaceuticals, Inc. (US) 2001-05-30 EP claimed
CN-1061666-C Method for atmospheric prepn. of polyarylthio-ether by using Na hydrosulfide UNIV SICHUAN UNITED (CN) 2001-02-07 CN claimed
WO-2000001683-A1 METHODS FOR SYNTHESIS OF SUBSTITUTED TETRAHYDROFURAN COMPOUND LEUKOSITE, INC. (US) 2000-01-13 WO claimed
CN-1145375-A Method for atmospheric prepn. of polyarylthio-ether by using Na hydrosulfide UNIV SICHUAN UNITED (CN) 1997-03-19 CN claimed
CN-1143652-A Method for preparing polyarylene sulfide with high molecular and high toughness UNIV SICHUAN UNION (CN) 1997-02-26 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035278-A1 Methods for synthesis of substituted tetrahydrofuran compound DHFR, CYP3A4, CYP3A5 SOS1 3840/4885HSPB1 3449/4885SCN4A 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.