SCHEMBL7938159

SCHEMBL7938159

O=S(=O)(c1ccccc1)c1ccc(Oc2ccc(O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.63
NR1H2 P55055 1/20 0.63
BAX Q07812 1/20 0.63
HTT P42858 2/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
GAA P10253 2/20 0.61
PKM P14618 1/20 0.61
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
HTR6 P50406 1/20 0.54
SOS1 Q07889 1/20 0.53
ELANE P08246 1/20 0.53
MMP2 P08253 2/20 0.49
MMP3 P08254 2/20 0.49
MMP9 P14780 2/20 0.49
MMP8 P22894 2/20 0.49
MMP14 P50281 2/20 0.49
MMP12 P39900 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24445611 1.00 LTA4H (0.63) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL18678670 1.00 LTA4H (0.63) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL24445604 1.00 LTA4H (0.63) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL416827 0.96 LTA4H (0.69) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL23430824 0.96 LTA4H (0.69) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL24445613 0.95 HTT (0.57) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL24445992 0.95 HTT (0.57) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL10052249 0.95 HTT (0.57) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL5848771 0.92 PKM (0.70) LTA4HNR1H2BAXHTTSMN1; SMN2
SCHEMBL8071139 0.92 PKM (0.70) LTA4HNR1H2BAXHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850033-B1 POLYARYLENE ETHER SULFONE BASF SE (DE) 2023-05-17 EP disclosed
EP-3850032-B1 POLYARYLENE ETHER BASF SE (DE) 2022-05-25 EP disclosed
EP-3577164-B1 POLYARYLENE ETHER SULFONE COMPRISING NAPHTHALIC ACID ANHYDRIDE ENDGROUPS BASF SE (DE) 2021-06-02 EP disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed