Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157609 | 0.88 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPDK1 | |
| SCHEMBL1157361 | 0.88 | PDK1 (0.43) | PDE4APDE4BPDE4CPDE4DPDK1 | |
| SCHEMBL4190538 | 0.86 | ALDH1A1 (0.55) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL1157560 | 0.84 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DPDK1 | |
| SCHEMBL1157694 | 0.82 | GRM2 (0.51) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL3132226 | 0.82 | PDE4B (0.43) | PDE4APDE4BPDE4CPDE4DPDK1 | |
| SCHEMBL4190655 | 0.82 | ALDH1A1 (0.50) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL1157867 | 0.81 | GRM2 (0.52) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL3192115 | 0.81 | MEN1 (0.48) | PDE4APDE4BPDE4CPDE4DPDK1 | |
| SCHEMBL1157487 | 0.81 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |