Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289878 | 0.97 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6293197 | 0.97 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6293224 | 0.97 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6290410 | 0.97 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6289927 | 0.97 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6290496 | 0.95 | ALDH1A1 (0.54) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6289347 | 0.95 | ALDH1A1 (0.54) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL8416223 | 0.93 | LTA4H (0.57) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6293128 | 0.93 | SMN1; SMN2 (0.58) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL6290588 | 0.93 | SMN1; SMN2 (0.58) | MAPTALDH1A1MEN1MITFGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114940659-A | Purification method of vitamin A miscellaneous oil | 万华化学(四川)有限公司 | 2022-08-26 | — | — | CN | disclosed |
| US-10300066-B2 | Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2019-05-28 | — | — | US | disclosed |
| US-20180207161-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2018-07-26 | — | — | US | disclosed |
| US-9861636-B2 | Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2018-01-09 | — | — | US | disclosed |
| US-20170065594-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2017-03-09 | — | — | US | disclosed |
| US-9532990-B2 | Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2017-01-03 | — | — | US | disclosed |
| US-20160200730-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2016-07-14 | — | — | US | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
| CN-1223656-A | Spiro-piperidine derivatives and their use as therapeutic agents | MERCK SHARP & DOHME (GB) | 1999-07-21 | — | — | CN | disclosed |
| WO-1999007750-A1 | PERFLUORINATED RESINS AS A SUPPORT FOR SOLID PHASE REACTIONS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 1999-02-18 | — | — | WO | disclosed |
| EP-0162606-B1 | AROMATIC POLYTHIOETHERAMIDES AND PROCESS FOR THEIR PRODUCTION | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |
| EP-0135938-B1 | PROCESS FOR PRODUCING AROMATIC POLYETHER KETONES AND POLYTHIOETHER KETONES | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4707536-A | Catalytic preparation of aromatic polyketone from phosgene and aromatic ether or sulfide | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-11-17 | — | — | US | disclosed |
| US-4661581-A | REACTING AROMATIC ETHERS OR THIOETHERS WITH PHOSGENE IN AN APROTIC SOLVENT WITH GROUP 3 METAL HALIDE CATALYST | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1987-04-28 | — | — | US | disclosed |
| US-4621134-A | Aromatic polythioetheramide | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0162606-A1 | Aromatic polythioetheramides and process for their production | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| EP-0135938-A2 | Process for producing aromatic polyether ketones and polythioether ketones | MITSUBISHI KASEI CORPORATION (JP) | 1985-04-03 | — | — | EP | disclosed |
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200730-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | BTK, LCK, LYN | MAPT 4188/4885ALDH1A1 3066/4885MEN1 4301/4885 |
| US-20170065594-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | BTK, LCK, LYN | MAPT 4188/4885ALDH1A1 3066/4885MEN1 4301/4885 |
| US-20180207161-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | BTK, LCK, LYN | MAPT 4188/4885ALDH1A1 3066/4885MEN1 4301/4885 |
| US-10300066-B2 | Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors | BTK, LCK, LYN | MAPT 4188/4885ALDH1A1 3066/4885MEN1 4301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.