Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544731 | 0.84 | HPGD (0.55) | ALDH1A1ALOX15HPGDUSP2TSHR | |
| SCHEMBL9860903 | 0.84 | HPGD (0.55) | ALDH1A1ALOX15HPGDUSP2TSHR | |
| SCHEMBL106507 | 0.83 | HPGD (0.44) | ALDH1A1ALOX15HPGDUSP2TSHR | |
| SCHEMBL4847445 | 0.83 | TSHR (0.52) | ALDH1A1HPGDUSP2TSHRKMT2A | |
| SCHEMBL1774412 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ALOX15HPGDUSP2TSHR | |
| SCHEMBL27775492 | 0.81 | KMT2A (0.50) | ALDH1A1HPGDUSP2TSHRKMT2A | |
| SCHEMBL967909 | 0.79 | CYP3A4 (0.44) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL9712390 | 0.79 | HPGD (0.42) | ALDH1A1ALOX15HPGDUSP2CES2 | |
| SCHEMBL27853419 | 0.76 | NOTUM (0.44) | ALDH1A1ALOX15HPGDUSP2CES2 | |
| SCHEMBL27853410 | 0.76 | CLCN2 (0.39) | ALDH1A1ALOX15CES2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922693-B1 | Process for the preparation of 3-chloro-4-fluorobenzoyl chloride | CLARIANT GMBH (DE) | 2001-10-24 | — | — | EP | disclosed |
| US-6187952-B1 | Two-step production of 3-chloro-4-fluoro-benzoyl chloride by chlorination | CLARIANT GMBH (DE) | 2001-02-13 | — | — | US | disclosed |
| EP-0922693-A1 | Process for the preparation of 3-chloro-4-fluorobenzoyl chloride | Clariant GmbH (DE) | 1999-06-16 | — | — | EP | disclosed |