Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 7/20 | 0.49 |
| ▸ | ACLY | P53396 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793762 | 0.89 | PFKFB3 (0.47) | PFKFB3MAPTLMNATP53THRB | |
| SCHEMBL793284 | 0.86 | ALDH1A1 (0.52) | PFKFB3MAPTKMT2ALNPEPRAB9A | |
| SCHEMBL794260 | 0.86 | PFKFB3 (0.53) | PFKFB3MAPTLMNAKMT2ALNPEP | |
| SCHEMBL794222 | 0.85 | PFKFB3 (0.56) | PFKFB3LNPEPPFKFB4 | |
| SCHEMBL794362 | 0.85 | PFKFB3 (0.68) | PFKFB3MAPTLMNATP53THRB | |
| SCHEMBL793550 | 0.85 | MAPT (0.56) | PFKFB3MAPTLMNATP53THRB | |
| SCHEMBL792880 | 0.84 | PFKFB3 (0.54) | PFKFB3MAPTLMNATP53THRB | |
| SCHEMBL794311 | 0.83 | PFKFB3 (0.65) | PFKFB3MAPTLMNATP53THRB | |
| SCHEMBL793409 | 0.82 | PFKFB3 (0.55) | PFKFB3ACLYLMNATHRBKMT2A | |
| SCHEMBL793555 | 0.81 | PFKFB3 (0.66) | PFKFB3MAPTLMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-A2 | SULFONAMIDE COMPOUNDS | Kancera AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035171-A2 | NEW COMPOUNDS | KANCERA AB (SE) | 2012-03-22 | — | — | WO | disclosed |