Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR1E | P28566 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833378 | 0.91 | TDP1 (0.37) | TDP1 | |
| SCHEMBL4306829 | 0.90 | TDP1 (0.35) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5697813 | 0.89 | CYP2C19 (0.46) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9699428 | 0.85 | TDP1 (0.33) | TDP1OPRK1 | |
| SCHEMBL11074655 | 0.84 | TDP1 (0.35) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13281660 | 0.79 | TDP1 (0.35) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10481680 | 0.79 | PRMT3 (0.42) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5826308 | 0.79 | KDM4E (0.38) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL127488 | 0.78 | TSHR (0.38) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2050506 | 0.77 | KDM4E (0.37) | TDP1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070723-A1 | Aminophosphonium compounds | Clariant GmbH (DE) | 2001-01-24 | — | — | EP | disclosed |