Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137319 | 0.89 | HDAC1 (0.76) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL15397972 | 0.79 | HDAC1 (0.69) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4581935 | 0.78 | HDAC1 (0.79) | HDAC1HDAC2HDAC3 | |
| SCHEMBL8291936 | 0.78 | HDAC2 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7934855 | 0.77 | HDAC1 (0.80) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11192637 | 0.77 | NPC1 (0.65) | ATR | |
| SCHEMBL29611891 | 0.77 | NPC1 (0.65) | ATR | |
| SCHEMBL7944495 | 0.77 | HDAC1 (0.58) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2606701 | 0.77 | HDAC1 (0.58) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4578711 | 0.76 | HDAC1 (0.84) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065117-A1 | INHIBITION OF HDAC2 TO PROMOTE MEMORY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-06-10 | — | — | WO | disclosed |