Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | CNR2 | P34972 | 8/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350574 | 0.87 | MEN1 (0.50) | MEN1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL7945014 | 0.87 | SLC6A9 (0.34) | MEN1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL1349461 | 0.79 | SLC6A9 (0.43) | MEN1KMT2ACNR1CNR2SLC6A9 | |
| SCHEMBL3261922 | 0.77 | SLC6A9 (0.44) | MEN1KMT2ASLC6A9ALDH1A1 | |
| SCHEMBL1348525 | 0.76 | SLC6A9 (0.45) | MEN1KMT2ASLC6A9ALDH1A1 | |
| SCHEMBL1350491 | 0.76 | SLC6A9 (0.48) | MEN1KMT2ASLC6A9 | |
| SCHEMBL1349997 | 0.76 | SLC6A9 (0.39) | MEN1KMT2ASLC6A9 | |
| SCHEMBL3237489 | 0.76 | SLC6A9 (0.50) | CNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL4355395 | 0.72 | SLC6A9 (0.44) | KMT2ASLC6A9ALDH1A1ATM | |
| SCHEMBL7937623 | 0.71 | TACR1 (0.32) | SLC6A9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020548-A1 | GLYT1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-02-25 | — | — | WO | disclosed |