Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MTTP | P55157 | 4/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350402 | 0.79 | MTTP (0.45) | CYP1A2CYP2D6CYP2C9SLC6A9MTTP | |
| SCHEMBL1348399 | 0.74 | SLC6A9 (0.50) | SLC6A9MTTP | |
| SCHEMBL7938683 | 0.71 | MEN1 (0.39) | SLC6A9NPC1 | |
| SCHEMBL1348590 | 0.70 | SLC6A9 (0.49) | SLC6A9MTTP | |
| SCHEMBL1350222 | 0.70 | SLC6A9 (0.49) | SLC6A9MTTP | |
| SCHEMBL1349648 | 0.70 | SLC6A9 (0.44) | SLC6A9 | |
| SCHEMBL1349947 | 0.70 | KLRK1 (0.41) | SLC6A9MTTP | |
| SCHEMBL1349793 | 0.70 | SLC6A9 (0.52) | SLC6A9LMNA | |
| SCHEMBL1349364 | 0.69 | SLC6A9 (0.53) | SLC6A9NPC1MTTPHPGD | |
| SCHEMBL1347772 | 0.69 | SLC6A9 (0.53) | CYP2D6SLC6A9MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020548-A1 | GLYT1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-02-25 | — | — | WO | disclosed |