Ethylbenzene

Ethylbenzene

SCHEMBL7938713

CCO[SiH](C)OCC.CCc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.61
ALDH1A1 P00352 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
TSHR P16473 1/20 0.36
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
POLB P06746 1/20 0.35
CALM1 P0DP23 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TAS2R14 Q9NYV8 1/20 0.34
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809342 0.85 TSHR (0.44) TP53ALDH1A1TSHRCYP1A2
Ethylbenzene SCHEMBL6889785 0.84 TP53 (0.64) TP53ALDH1A1PPARGPPARATSHR
Biphenyl SCHEMBL28295625 0.82 ALDH1A1 (0.43) TP53ALDH1A1RAB9ASMN1; SMN2
Ethylbenzene SCHEMBL11223212 0.78 TP53 (1.00) TP53ALDH1A1TSHRRAB9ASMN1; SMN2
Ethylbenzene SCHEMBL7458207 0.78 TP53 (1.00) TP53ALDH1A1TSHRRAB9ASMN1; SMN2
Ethylbenzene SCHEMBL3987542 0.78 TP53 (1.00) TP53ALDH1A1TSHRRAB9ASMN1; SMN2
Ethylbenzene SCHEMBL1330604 0.78
Ethylbenzene SCHEMBL1332452 0.78
Ethylbenzene SCHEMBL1331299 0.78
Ethylbenzene SCHEMBL27454352 0.78 TP53 (1.00) TP53ALDH1A1TSHRRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601496-B2 Process for the preparation of olefin polymer MITSUI CHEMICALS INC (JP) 2001-06-27 EP disclosed