Biphenyl

Biphenyl

SCHEMBL28295625

CCO[SiH](C)OCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
SLC6A4 P31645 1/20 0.36
TAAR1 Q96RJ0 2/20 0.35
IDO1 P14902 2/20 0.35
AGXT P21549 2/20 0.35
LTA4H P09960 1/20 0.35
HPGD P15428 3/20 0.35
TP53 P04637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CHRNB2 P17787 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL3480054 0.83 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2L3MBTL1MAPTNPC1
Ethylbenzene SCHEMBL7938713 0.82 TP53 (0.61) ALDH1A1SMN1; SMN2RAB9ATP53
SCHEMBL19809342 0.80 TSHR (0.44) ALDH1A1L3MBTL1MAPTIDO1AGXT
SCHEMBL5598837 0.79 TSHR (0.56) ALDH1A1SMN1; SMN2L3MBTL1MAPTLTA4H
SCHEMBL19927500 0.77 LTA4H (0.42) L3MBTL1LTA4HTP53CHRNB2CHRNB4
SCHEMBL16487201 0.76 TAAR1 (0.40) ALDH1A1SMN1; SMN2L3MBTL1MAPTNPC1
SCHEMBL35695 0.76
SCHEMBL29007128 0.74 ALDH1A1 (0.39) ALDH1A1
Biphenyl SCHEMBL8192900 0.74 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2L3MBTL1MAPTNPC1
Biphenyl SCHEMBL1147617 0.74 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2L3MBTL1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716544-A LED Encapulant composition 日产化学株式会社 2019-05-03 CN disclosed