Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757392 | 0.83 | EPHX2 (0.40) | EPHX2PDK2ACMSDBACE1KMT2A | |
| SCHEMBL714541 | 0.81 | EPHX2 (0.41) | EPHX2PDK2ACMSDBACE1KMO | |
| SCHEMBL16393610 | 0.80 | ALDH1A1 (0.53) | PDK2MAPTAKR1A1AKR1B1HTT | |
| SCHEMBL27862643 | 0.79 | EPHX2 (0.40) | EPHX2PDK2ACMSDBACE1KMO | |
| SCHEMBL9746450 | 0.79 | EPHX2 (0.49) | EPHX2PDK2ACMSDBACE1KMO | |
| SCHEMBL10879536 | 0.79 | EPHX2 (0.49) | EPHX2PDK2ACMSDBACE1KMO | |
| Hydrochloric Acid SCHEMBL27998359 | 0.78 | EPHX2 (0.40) | EPHX2PDK2ACMSDBACE1KMO | |
| SCHEMBL3561526 | 0.76 | EPHX2 (0.66) | EPHX2 | |
| SCHEMBL714542 | 0.75 | ACMSD (0.43) | EPHX2PDK2ACMSDBACE1KMO | |
| SCHEMBL24125875 | 0.74 | EPHX2 (0.53) | EPHX2ACMSDKMOKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666267-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0666267-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-04-18 | — | — | EP | disclosed |
| CN-1060176-C | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-01-03 | — | — | CN | disclosed |
| US-5571880-A | CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0666267-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-09 | — | — | EP | disclosed |