Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897001 | 0.85 | ELAVL1 (0.37) | MEN1KMT2AMAPTKDM4EUSP2 | |
| SCHEMBL3005126 | 0.77 | KDM4E (0.32) | KDM4EALDH1A1POLBTYMS | |
| SCHEMBL23599373 | 0.74 | CYP3A4 (0.41) | MEN1KMT2AMAPTKDM4EELAVL1 | |
| SCHEMBL31185504 | 0.74 | CYP3A4 (0.41) | MEN1KMT2AMAPTKDM4EELAVL1 | |
| SCHEMBL20691958 | 0.72 | BRD4 (0.37) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17397694 | 0.71 | ACLY (0.45) | MEN1KMT2AMAPTKDM4EUSP2 | |
| SCHEMBL30994051 | 0.71 | ACLY (0.45) | MEN1KMT2AMAPTKDM4EUSP2 | |
| SCHEMBL11917771 | 0.71 | PBRM1 (0.41) | MEN1KMT2AMAPTKDM4EUSP2 | |
| SCHEMBL11927529 | 0.71 | TYMS (0.42) | MEN1KMT2AMAPTKDM4EUSP2 | |
| SCHEMBL9579461 | 0.71 | MAOA (0.47) | MEN1KMT2AMAPTKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | disclosed |
| EP-0865419-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | Venantius Limited (IE) | 1998-09-23 | — | — | EP | disclosed |