Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938457 | 0.88 | MAPT (0.67) | MEN1KMT2AMAPT | |
| SCHEMBL7936274 | 0.85 | MEN1 (0.56) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6813782 | 0.85 | MEN1 (0.52) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL7847389 | 0.84 | MEN1 (0.49) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6698319 | 0.84 | MEN1 (0.50) | MEN1KMT2AMAPT | |
| SCHEMBL6699566 | 0.81 | MEN1 (0.48) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL7940926 | 0.80 | MEN1 (0.53) | MEN1KMT2AMAPTF2LMNA | |
| SCHEMBL6695126 | 0.77 | KMT2A (0.48) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL7845700 | 0.76 | NHERF1 (0.61) | MEN1KMT2AMAPTADORA2AADORA1 | |
| SCHEMBL7846930 | 0.76 | MAPT (0.53) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |