Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938457 | 0.88 | MAPT (0.67) | MAPTMEN1KMT2ARXFP1TP53 | |
| SCHEMBL6668328 | 0.82 | MAPT (0.49) | MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL6694423 | 0.81 | MEN1 (0.60) | MAPTMEN1KMT2ATP53KCNH2 | |
| SCHEMBL6814897 | 0.76 | MAPT (0.68) | MAPTMEN1KMT2ARXFP1TP53 | |
| SCHEMBL7842626 | 0.76 | MAPT (0.68) | MAPTMEN1KMT2ARXFP1TP53 | |
| SCHEMBL7938895 | 0.76 | MEN1 (0.52) | MAPTMEN1KMT2A | |
| SCHEMBL6813782 | 0.75 | MEN1 (0.52) | MAPTMEN1KMT2A | |
| SCHEMBL13774353 | 0.74 | ALDH1A1 (0.45) | MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL6695126 | 0.73 | KMT2A (0.48) | MAPTMEN1KMT2ARXFP1POLB | |
| SCHEMBL7936274 | 0.73 | MEN1 (0.56) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |