SCHEMBL7939072

SCHEMBL7939072

C=CCc1ccc2cc(-c3cnc(/C=C/CCCC(C)F)nc3)ccc2c1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.32
PTGS2 P35354 1/20 0.31
ALOX5 P09917 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7939077 1.00 CNR2 (0.32) CNR2PTGS2ALOX5GABRA1GABRB2
SCHEMBL8598611 0.90 PTGS2 (0.31) PTGS2
SCHEMBL8598607 0.90 PTGS2 (0.31) PTGS2
SCHEMBL7555273 0.89 CNR2 (0.31) CNR2
SCHEMBL7555276 0.89 CNR2 (0.31) CNR2
SCHEMBL7559045 0.85 ALDH1A1 (0.30)
SCHEMBL7558965 0.85 SRC (0.42)
SCHEMBL7559040 0.85 ALDH1A1 (0.30)
SCHEMBL7558968 0.85 SRC (0.42)
SCHEMBL7557688 0.85 PTGS2 (0.35) CNR2PTGS2ALOX5GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6246452-B1 FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE HAVING IMPROVED RESPONSE SPEED WHICH CAN BE USED AS AN OPTICAL SHUTTER OR DISPLAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-12 US disclosed
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0708165-A1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-24 EP disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed