Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3041073 | 0.97 | PNMT (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| Iodide SCHEMBL7921884 | 0.97 | PNMT (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29695725 | 0.78 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8379134 | 0.78 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL816978 | 0.78 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL9412846 | 0.77 | MAPT (0.39) | NPC1RAB9ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4890082 | 0.72 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL27348144 | 0.72 | PNMT (0.45) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28220071 | 0.71 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28286932 | 0.71 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946610-B1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXONMOBIL CHEM PATENTS INC (US) | 2001-11-28 | — | — | EP | disclosed |