Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.30 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7921884 | 0.97 | PNMT (0.39) | PNMTNPC1RAB9ADRD2DRD4 | |
| Bromide SCHEMBL7939131 | 0.97 | PNMT (0.39) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL29695725 | 0.81 | PNMT (0.50) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL816978 | 0.81 | PNMT (0.50) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9412846 | 0.79 | MAPT (0.39) | NPC1RAB9ADRD2DRD3MAP3K9 | |
| SCHEMBL8379134 | 0.78 | PNMT (0.50) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4890082 | 0.75 | PNMT (0.37) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL27425148 | 0.73 | PNMT (0.42) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL27348144 | 0.72 | PNMT (0.45) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL28220071 | 0.71 | PNMT (0.44) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736358-A | Metallocene polyethylene for sintering and preparation method and application thereof | 上海化工研究院有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-20230141606-A1 | Alkylation of Transition Metal Coordination Catalyst Complexes | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2021194831-A1 | ALKYLATION OF TRANSITION METAL COORDINATION CATALYST COMPLEXES | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| EP-1880986-B1 | PROCESS FOR PRODUCING SATURATED ALIPHATIC HYDROCARBONS, AND LUBRICANT COMPOSITIONS THEREOF | IDEMITSU KOSAN CO (JP) | 2013-03-06 | — | — | EP | disclosed |
| EP-2222723-B1 | METHOD FOR CONTROLLING BIMODAL CATALYST ACTIVITY DURING POLYMERIZATION | UNIVATION TECH LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-8373011-B2 | Used in a base oil of lubricant having good low temperature fluidity, low evaporativity, and thermal stability and oxidation stability | IDEMITSU KOSAN CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8318872-B2 | Method for controlling bimodal catalyst activity during polymerization | UNIVATION TECHNOLOGIES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| EP-2222723-A2 | METHOD FOR CONTROLLING BIMODAL CATALYST ACTIVITY DURING POLYMERIZATION | Univation Technologies, LLC (US) | 2010-09-01 | — | — | EP | disclosed |
| US-7785735-B2 | Microporous composite membrane and its producing method and use | TONEN CHEMICAL CORPORATION (JP) | 2010-08-31 | — | — | US | disclosed |
| EP-1693408-B1 | MICROPOROUS COMPOSITE FILM, PROCESS FOR PRODUCING THE SAME, AND USE | TONEN SEKIYUKAGAKU KK (JP) | 2010-04-14 | — | — | EP | disclosed |
| WO-1998037101-A1 | IMPROVED CONTROL OF SOLUTION CATALYST DROPLET SIZE WITH AN EFFERVESCENT SPRAY NOZZLE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |
| WO-1998030608-A1 | METHOD OF CONTROLLING OLEFIN POLYMERIZATION CATALYST COMPOSITION ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| WO-1998030606-A1 | OLEFIN POLYMERIZATION CATALYST COMPOSITION HAVING INCREASED ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| WO-1998028350-A1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXON CHEMICAL PATENTS INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| EP-0811637-A2 | Method for feeding a liquid catalyst to a fluidized bed polmerization reactor | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0811638-A2 | Process for controlling static in polymerizations utilizing metallocene catalysts | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5693727-A | INTRODUCING MONOMERS INTO POLYMERIZATION ZONE CONTAINING BED OF GROWING POLYMER PARTICLES, INTRODUCING UNSUPPORTED POLYMERIZATION CATALYST IN LIQUID FORM INTO VESSEL, WITHDRAWING POLYMERIC PRODUCT, UNREACTED MONOMERS, GASES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0768320-A1 | Catalyst component and catalyst | NIPPON OIL CO. LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5476914-A | Highly crystalline; comprising a high percentage of racemic dyads | FINA TECHNOLOGY, INC. (US) | 1995-12-19 | — | — | US | disclosed |
| US-5132381-A | Aluminoxane, Hafnium Metallocene | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230141606-A1 | Alkylation of Transition Metal Coordination Catalyst Complexes | AS3MT, AP1M1, AP3M1 | PNMT 1288/4885NPC1 1405/4885RAB9A 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.