⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865721 | 0.80 | — | — | |
| SCHEMBL681184 | 0.78 | ELANE (0.34) | — | |
| Ethylene Glycol Diisobutanoate SCHEMBL843146 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL31349332 | 0.76 | MAPT (0.32) | — | |
| SCHEMBL27542631 | 0.75 | — | — | |
| SCHEMBL79434 | 0.75 | — | — | |
| SCHEMBL216117 | 0.75 | — | — | |
| SCHEMBL80284 | 0.75 | — | — | |
| SCHEMBL30902202 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL22597524 | 0.75 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925640-B | ((3-Carbamoyl-5-fluoropyrazin-2-yl) oxy) methyl isobutyrate and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-115925640-A | ((3-carbamoyl-5-fluoropyrazin-2-yl) oxy) methyl isobutyrate and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-04-07 | — | — | CN | claimed |
| US-12637481-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| CN-115925640-B | ((3-Carbamoyl-5-fluoropyrazin-2-yl) oxy) methyl isobutyrate and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-03-28 | — | — | CN | disclosed |
| CN-118541355-A | Solid forms of a compound, methods of preparation and uses thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-08-23 | — | — | CN | disclosed |
| US-20240209014-A1 | NOVEL SPINOSYN PRODRUGS | ACIES BIO D.O.O. (SI) | 2024-06-27 | — | — | US | disclosed |
| US-20240209014-A1 | NOVEL SPINOSYN PRODRUGS | ACIES BIO D.O.O. (SI) | 2024-06-27 | — | — | US | disclosed |
| CN-116687932-B | Medical application of ((3-carbamoyl-5-fluoropyrazin-2-yl) oxy) methyl isobutyrate | 中国人民解放军军事科学院军事医学研究院 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023169119-A1 | SOLID FORM OF COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2023-09-14 | — | — | WO | disclosed |
| CN-116687932-A | Medical application of ((3-carbamoyl-5-fluoropyrazin-2-yl) oxy) methyl isobutyrate | 中国人民解放军军事科学院军事医学研究院 | 2023-09-05 | — | — | CN | disclosed |
| US-20230151029-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA, INC. | 2023-05-18 | — | — | US | disclosed |
| WO-2013009791-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-01-17 | — | — | WO | disclosed |
| US-20130019348-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-01-17 | — | — | US | disclosed |
| CN-1420881-A | Beta-amino acid derivs. as inhibitors of matrix metalloproteases and TNF-alpha | BRISTOL MYERS SQUIBB PHARMACEU (US) | 2003-05-28 | — | — | CN | disclosed |
| US-6239145-B1 | USABLE IN ACQUIRING INFORMATION ABOUT ACTIVE OXYGEN OR IN VIVO FREE RADICALS AS BIOLOGICAL IMAGES SUCH AS MAGNETIC RESONANCE IMAGES OR MAGNETOENCEPHALOGRAMS; | DAIITCHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0995740-A1 | NOVEL NITROXYL COMPOUNDS AND DRUGS AND REAGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-4716158-A | CEPHALOSPORINS SUITABLE FOR ORAL ADMINISTRATION | SANKYO COMPANY LIMITED (JP) | 1987-12-29 | — | — | US | disclosed |
| EP-0049118-B1 | CEPHALOSPORIN DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| US-4486425-A | ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1984-12-04 | — | — | US | disclosed |
| EP-0049118-A2 | Cephalosporin derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |