SCHEMBL7939206

SCHEMBL7939206

C=C(COCC(C(=O)O)=C(C1CCC(C(C)(C)C)CC1)C1CCC(C(C)(C)C)CC1)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.37
HSD11B1 P28845 1/20 0.34
ALDH1A1 P00352 5/20 0.34
MAPT P10636 3/20 0.34
RECQL P46063 2/20 0.33
ATM Q13315 1/20 0.33
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 2/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
LIPA P38571 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7939208 0.71 APOBEC3A (0.35) GLAHSD11B1ALDH1A1MAPTRECQL
SCHEMBL195867 0.71 TET2 (0.37)
SCHEMBL8057709 0.69 APOBEC3A (0.44) HSD11B1ALDH1A1MAPTRECQLATM
SCHEMBL195078 0.69 GRIK1 (0.39)
SCHEMBL692291 0.68 GLA (0.45) GLAHSD11B1ALDH1A1MAPTRECQL
SCHEMBL195104 0.68 GRIK1 (0.35)
SCHEMBL1450333 0.67 LIPA (0.53) GLAHSD11B1MAPTAPOBEC3AAPOBEC3G
SCHEMBL194838 0.67 TET2 (0.34)
SCHEMBL4611862 0.67 TP53 (0.32)
SCHEMBL351637 0.67 TET2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6262214-B1 TRANSPARENCY, HEAT-RESISTANCE AND MECHANICAL STRENGTH; USED TO MAKE LENSES, OPTICAL DISKS, OPTICAL FIBERS MITSUBISHI RAYON CO., LTD. (JP) 2001-07-17 US disclosed
EP-0936227-A1 LOWLY BIREFRINGENT POLYMER, PROCESS FOR THE PRODUCTION THEREOF, AND OPTICAL PICKUP LENS MITSUBISHI RAYON CO., LTD. (JP) 1999-08-18 EP disclosed