Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367820 | 0.88 | ALDH1A1 (0.61) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL31503975 | 0.83 | LMNA (0.78) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL4913667 | 0.82 | HCAR2 (0.65) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL2956119 | 0.81 | HIF1A (0.67) | NPC1RAB9AMITFKLF5MEN1 | |
| SCHEMBL3498895 | 0.80 | LMNA (0.78) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL9269038 | 0.80 | KMT2A (0.66) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL14113481 | 0.79 | NPC1 (0.48) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL3301439 | 0.79 | NPC1 (0.48) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL3301443 | 0.79 | NPC1 (0.48) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL20495111 | 0.78 | HIF1A (0.63) | GAAMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245817-B1 | NEUROPEPTIDE Y | BAYER CORPORATION | 2001-06-12 | — | — | US | disclosed |
| US-5939462-A | ADMINISTERING ALKOXY AND -THIOALKOXYAMIDE COMPOSITIONS TO MAMMALS TO TREAT DISORDERS SUCH AS OBESITY THAT ARE MEDIATED BY NEUROPEPTIDE Y (?NPY?) | BAYER CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |