Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 12/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 12/20 | 0.41 |
| ▸ | WDR5 | P61964 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185268 | 0.89 | P2RX3 (0.49) | P2RX3P2RX2WDR5L3MBTL1PIK3CA | |
| SCHEMBL2185316 | 0.89 | P2RX3 (0.39) | P2RX3P2RX2WDR5L3MBTL1PIK3CA | |
| SCHEMBL7950915 | 0.86 | WDR5 (0.43) | P2RX3P2RX2WDR5PIK3CAKDM1A | |
| SCHEMBL7947046 | 0.78 | P2RX3 (0.50) | P2RX3P2RX2WDR5 | |
| SCHEMBL2185262 | 0.77 | P2RX3 (0.51) | P2RX3P2RX2WDR5L3MBTL1 | |
| SCHEMBL2171537 | 0.77 | P2RX3 (0.51) | P2RX3P2RX2WDR5L3MBTL1 | |
| SCHEMBL7997679 | 0.77 | WDR5 (0.43) | P2RX3P2RX2WDR5PIK3CAKDM1A | |
| SCHEMBL2185479 | 0.76 | WDR5 (0.41) | P2RX3P2RX2WDR5 | |
| SCHEMBL8011606 | 0.75 | WDR5 (0.45) | P2RX3P2RX2WDR5PIK3CAKDM1A | |
| SCHEMBL2186337 | 0.75 | P2RX3 (0.49) | P2RX3P2RX2WDR5PIK3CAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |