Syringol

Syringol

SCHEMBL7939422

CC1=C([Zr+2]C2c3ccccc3-c3ccccc32)C(C)C=C1.COc1cccc(OC)c1[O-].COc1cccc(OC)c1[O-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.33
ACHE P22303 1/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
KMT2A Q03164 1/20 0.32
TOP1 P11387 1/20 0.31
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
NR3C1 P04150 1/20 0.30
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
TP53 P04637 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4537631 0.83 GPR3 (0.32)
Syringol SCHEMBL7939421 0.73 KDM4E (0.34) ACHEMEN1KMT2AKDM4EGAA
Syringol SCHEMBL7929842 0.71 POLL (0.33) CYP19A1ACHENR3C1GAA
Syringol SCHEMBL7942003 0.66 MEN1 (0.35) MEN1USP2KMT2ATOP1KDM4E
Syringol SCHEMBL7930232 0.64
Hydrochloric Acid SCHEMBL7549765 0.62 NR3C1 (0.38) CYP19A1ACHEMEN1USP2KMT2A
Syringol SCHEMBL6049239 0.62 CA1 (0.55) TOP1KDM4ELMNATP53HTT
Hydrochloric Acid SCHEMBL2841029 0.61
Hydrochloric Acid SCHEMBL16424365 0.61 NR3C1 (0.36) CYP19A1MEN1USP2KMT2ATOP1
Hydrochloric Acid SCHEMBL2835340 0.61 CYP2E1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6281320-B1 POLYOLEFIN CATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-08-28 US disclosed