Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397419 | 0.82 | KMT2A (0.51) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL5249556 | 0.82 | KMT2A (0.51) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL8639463 | 0.81 | CYP1A2 (0.63) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL3111571 | 0.79 | KMT2A (0.56) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL538512 | 0.79 | KMT2A (0.60) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL3437801 | 0.79 | KMT2A (0.60) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL27750565 | 0.78 | LMNA (0.51) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL28594606 | 0.77 | KMT2A (0.58) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| Hydrochloric Acid SCHEMBL11895689 | 0.77 | KMT2A (0.58) | KMT2ALMNARAB9AFFAR1FFAR4 | |
| SCHEMBL29512995 | 0.77 | KMT2A (0.58) | KMT2ALMNARAB9AFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245817-B1 | NEUROPEPTIDE Y | BAYER CORPORATION | 2001-06-12 | — | — | US | disclosed |
| US-5939462-A | ADMINISTERING ALKOXY AND -THIOALKOXYAMIDE COMPOSITIONS TO MAMMALS TO TREAT DISORDERS SUCH AS OBESITY THAT ARE MEDIATED BY NEUROPEPTIDE Y (?NPY?) | BAYER CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0927166-A1 | AMIDES AS NPY5 RECEPTOR ANTAGONISTS | Bayer Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998035944-A1 | AMIDES AS NPY5 RECEPTOR ANTAGONISTS | BAYER CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |