Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939513 | 1.00 | HDAC4 (0.48) | HDAC4MEF2DHDAC1SCN9ACTSK | |
| SCHEMBL6555028 | 0.88 | KDM4E (0.56) | HDAC4MEF2DHDAC1CTSKCTSS | |
| SCHEMBL26436560 | 0.87 | LMNA (0.48) | HDAC4MEF2DHDAC1SCN9ACTSK | |
| SCHEMBL6892615 | 0.85 | CTSS (0.61) | SCN9ACTSKCTSSHDAC8MMP1 | |
| SCHEMBL27613652 | 0.82 | HDAC4 (0.61) | HDAC4HDAC1CTSKCTSSHDAC8 | |
| SCHEMBL27192808 | 0.81 | CTSS (0.55) | HDAC4MEF2DCTSKCTSSLMNA | |
| SCHEMBL27192669 | 0.81 | CTSS (0.55) | HDAC4MEF2DCTSKCTSSLMNA | |
| SCHEMBL7379924 | 0.80 | ANPEP (0.68) | MAPT | |
| SCHEMBL29695306 | 0.78 | NPC1 (0.58) | ALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL222110 | 0.78 | NPC1 (0.58) | ALDH1A1POLBRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |