Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 3/20 | 0.57 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947186 | 0.95 | BLM (0.53) | ERCC1ERCC4TSHRBLMNPSR1 | |
| SCHEMBL7939628 | 0.90 | TSHR (0.57) | TSHRBLMNPSR1CYP3A4ALOX15 | |
| SCHEMBL7947240 | 0.88 | TYR (0.57) | TSHRBLMNPSR1ALOX15KDM4E | |
| SCHEMBL7947252 | 0.87 | ERCC1 (0.65) | ERCC1ERCC4TRPV1 | |
| SCHEMBL8108684 | 0.82 | ALOX15 (0.59) | ERCC1ERCC4TSHRBLMNPSR1 | |
| SCHEMBL17667848 | 0.80 | CYP3A4 (0.60) | ERCC1ERCC4TSHRBLMNPSR1 | |
| SCHEMBL4947604 | 0.80 | CYP3A4 (0.60) | ERCC1ERCC4TSHRBLMNPSR1 | |
| SCHEMBL6364316 | 0.79 | ERCC1 (0.72) | ERCC1ERCC4TSHRCYP3A4ALOX15 | |
| SCHEMBL7939631 | 0.79 | ERCC1 (0.54) | ERCC1ERCC4TSHRBLMCYP3A4 | |
| SCHEMBL3872413 | 0.77 | CYP1A2 (0.57) | TSHRBLMNPSR1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265611-B1 | USE AS ANTIOXIDANTS OR FREE-RADICAL SCAVENGERS IN COSMETICS AND PHARMACEUTICALS AND FOODS | HAARMANN & REIMER GMBH (DE) | 2001-07-24 | — | — | US | claimed |
| EP-1029849-A1 | Hydroxymandelamides of phenolic amines | HAARMANN & REIMER GMBH (DE) | 2000-08-23 | — | — | EP | claimed |
| US-6265611-B1 | USE AS ANTIOXIDANTS OR FREE-RADICAL SCAVENGERS IN COSMETICS AND PHARMACEUTICALS AND FOODS | HAARMANN & REIMER GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-1029849-A1 | Hydroxymandelamides of phenolic amines | HAARMANN & REIMER GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |