Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939608 | 0.90 | ERCC1 (0.57) | TSHRBLMNPSR1GLSCYP3A4 | |
| SCHEMBL7947186 | 0.85 | BLM (0.53) | TSHRBLMNPSR1CYP3A4PMP22 | |
| SCHEMBL7939631 | 0.84 | ERCC1 (0.54) | TSHRBLMCYP3A4NFKB1KDM4E | |
| SCHEMBL7947240 | 0.81 | TYR (0.57) | TSHRBLMNPSR1GLSKDM4E | |
| SCHEMBL2121870 | 0.77 | NAAA (0.59) | TSHRBLMNPSR1 | |
| SCHEMBL5705007 | 0.77 | NAAA (0.59) | TSHRBLMNPSR1 | |
| SCHEMBL4876904 | 0.77 | NAAA (0.59) | TSHRBLMNPSR1 | |
| SCHEMBL7947252 | 0.76 | ERCC1 (0.65) | TRPV1 | |
| SCHEMBL13816533 | 0.75 | TSHR (0.73) | TSHRBLMNPSR1GLSCYP3A4 | |
| SCHEMBL17667848 | 0.75 | CYP3A4 (0.60) | TSHRBLMNPSR1CYP3A4PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265611-B1 | USE AS ANTIOXIDANTS OR FREE-RADICAL SCAVENGERS IN COSMETICS AND PHARMACEUTICALS AND FOODS | HAARMANN & REIMER GMBH (DE) | 2001-07-24 | — | — | US | claimed |
| EP-1029849-A1 | Hydroxymandelamides of phenolic amines | HAARMANN & REIMER GMBH (DE) | 2000-08-23 | — | — | EP | claimed |
| US-6265611-B1 | USE AS ANTIOXIDANTS OR FREE-RADICAL SCAVENGERS IN COSMETICS AND PHARMACEUTICALS AND FOODS | HAARMANN & REIMER GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-1029849-A1 | Hydroxymandelamides of phenolic amines | HAARMANN & REIMER GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |