Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936206 | 0.67 | NR4A1 (0.39) | IDO1ALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL20548576 | 0.67 | P2RX4 (0.38) | ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL29913613 | 0.65 | LMNA (0.46) | IDO1ALDH1A1MAPTHSD17B10MTNR1A | |
| SCHEMBL4556947 | 0.65 | ALDH1A1 (0.36) | IDO1ALDH1A1MAPTHSD17B10PKM | |
| SCHEMBL5859155 | 0.64 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDLMNAKDM4E | |
| SCHEMBL6167789 | 0.64 | ALDH1A1 (0.35) | IDO1ALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL4556946 | 0.64 | ACP3 (0.39) | ALDH1A1MAPTHSD17B10LMNAKDM4E | |
| SCHEMBL1505694 | 0.63 | ANPEP (0.41) | ALDH1A1HSD17B10ANPEPPAX8 | |
| SCHEMBL987554 | 0.62 | ALDH1A1 (0.34) | ALDH1A1HSD17B10HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL6230006 | 0.62 | ALDH1A1 (0.38) | IDO1ALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159245-A1 | SYNTHESIS OF 4-KETOCYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051958-A1 | SYNTHESIS OF 4-KETOCYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |