SCHEMBL7939743

SCHEMBL7939743

CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(-c3ccccc3Cl)c2C)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
HSP90AA1 P07900 1/20 0.33
GAA P10253 2/20 0.33
HTT P42858 2/20 0.33
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
USP28 Q96RU2 1/20 0.31
SHBG P04278 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946322 0.90 LMNA (0.41) SMN1; SMN2RAB9AALDH1A1LMNAGAA
SCHEMBL7949472 0.88 LMNA (0.35) SMN1; SMN2RAB9AALDH1A1LMNAL3MBTL1
SCHEMBL7946284 0.87 LMNA (0.34) SMN1; SMN2RAB9AALDH1A1LMNAL3MBTL1
SCHEMBL7951276 0.86 LMNA (0.38) SMN1; SMN2RAB9AALDH1A1LMNAGAA
SCHEMBL7939640 0.84 SMN1; SMN2 (0.39) SMN1; SMN2RAB9AALDH1A1LMNAGAA
SCHEMBL7948299 0.84 SMN1; SMN2 (0.41) SMN1; SMN2RAB9AALDH1A1LMNAGAA
SCHEMBL7949489 0.83 SMN1; SMN2 (0.37) SMN1; SMN2RAB9AALDH1A1LMNAL3MBTL1
SCHEMBL10872717 0.82 LMNA (0.38) SMN1; SMN2RAB9AALDH1A1LMNAGAA
SCHEMBL7947420 0.82 PTGS2 (0.35) SMN1; SMN2RAB9AALDH1A1LMNAGAA
SCHEMBL9448454 0.81 SMN1; SMN2 (0.40) SMN1; SMN2RAB9AALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265606-B1 TO CONTROL A BROAD SPECTRUM OF UNDESIRABLE VEGETATION, ARE SELECTIVE TO MAJOR CROPS, HAVE DESIRABLE ENVIRONMENTAL PROFILES, DOW AGROSCIENCES LLC 2001-07-24 US disclosed
US-6010981-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-01-04 US disclosed