Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032870 | 0.83 | PNMT (0.57) | PNMTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL1539790 | 0.81 | PNMT (0.55) | PNMTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL7455264 | 0.81 | PNMT (0.68) | PNMTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL7604159 | 0.80 | PNMT (0.54) | PNMTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL28836883 | 0.80 | PNMT (0.62) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL17801652 | 0.79 | PNMT (0.53) | PNMTDRD2DRD4DRD3CYP1A2 | |
| Hydrochloric Acid SCHEMBL7607175 | 0.79 | PNMT (0.53) | PNMTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL28904088 | 0.78 | PNMT (0.55) | PNMTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL18229939 | 0.78 | PNMT (0.51) | PNMTDRD2DRD4DRD3CYP1A2 | |
| SCHEMBL30606684 | 0.78 | PNMT (0.68) | PNMTDRD2DRD4DRD3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666267-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-04-18 | — | — | EP | disclosed |
| EP-0512554-B1 | Method for making cyclopentadiene type compounds | PHILLIPS PETROLEUM CO (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5571880-A | CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5541351-A | Cyclopentadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0666267-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5406013-A | Cyclopentadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5393911-A | Cyclopentadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5191132-A | CYCLOPENTADIENE TYPE COMPOUNDS AND METHOD FOR MAKING | PHILLIPS PETROLEUM COMPANY (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0512554-A2 | Cyclopetadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1992-11-11 | — | — | EP | disclosed |