Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504201 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL9395708 | 0.88 | GLO1 (0.56) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL7815000 | 0.86 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL7815086 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL4317965 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL7697999 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL1331989 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL9823358 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL7262 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL5611950 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10GLO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094292-B1 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR INC (US) | 2014-07-09 | — | — | EP | claimed |
| US-20120220529-A1 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR, INC. | 2012-08-30 | — | — | US | claimed |
| US-8129338-B2 | Nitric oxide-blocked cross-linked tetrameric hemoglobin | IKOR, INC. (US) | 2012-03-06 | — | — | US | claimed |
| US-20100035797-A1 | Nitric oxide-blocked cross-linked tetrameric hemoglobin | IKOR Inc., a South Dakota Corporation | 2010-02-11 | — | — | US | claimed |
| EP-2094292-A2 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | Ikor, Inc. (US) | 2009-09-02 | — | — | EP | claimed |
| US-7504377-B2 | Nitric oxide-blocked cross-linked tetrameric hemoglobin | IKOR, INC. (US) | 2009-03-17 | — | — | US | claimed |
| US-7494974-B2 | Carboxymethylated cross-linked tetrameric hemoglobin | IKOR, INC. (US) | 2009-02-24 | — | — | US | claimed |
| WO-2008051689-A2 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR, INC. (US) | 2008-05-02 | — | — | WO | claimed |
| US-20080096805-A1 | deoxygenated, endotoxin-free and stroma-free transport proteins, incapable of binding with nitric oxide, useful as substitutes for erythrocytes in mammals and for treating disorders where oxygen delivery agents are of benefit | IKOR, INC. | 2008-04-24 | — | — | US | claimed |
| US-20080096803-A1 | Carboxymethylated cross-linked tetrameric hemoglobin | IKOR, INC. | 2008-04-24 | — | — | US | claimed |
| US-6291620-B1 | Polymer synthesis | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-09-18 | — | — | US | claimed |
| EP-0791016-B1 | POLYMER SYNTHESIS | DU PONT (US) | 2000-07-12 | — | — | EP | claimed |
| WO-1996015157-A1 | POLYMER SYNTHESIS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-05-23 | — | — | WO | claimed |
| US-4479883-A | Lubricant composition with improved friction reducing properties containing a mixture of dithiocarbamates | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-10-30 | — | — | US | claimed |
| EP-2094292-B1 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR INC (US) | 2014-07-09 | — | — | EP | disclosed |
| US-20120220529-A1 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR, INC. | 2012-08-30 | — | — | US | disclosed |
| US-8129338-B2 | Nitric oxide-blocked cross-linked tetrameric hemoglobin | IKOR, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| EP-0433024-A1 | Colour recording medium containing leuco dye | FUJI PHOTO FILM CO., LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |
| US-4925590-A | Derivatives of 4-cyano-2,3-difluorophenol | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-05-15 | — | — | US | disclosed |
| US-4479883-A | Lubricant composition with improved friction reducing properties containing a mixture of dithiocarbamates | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-10-30 | — | — | US | disclosed |