SCHEMBL7940016

SCHEMBL7940016

CC(=O)O[C@H]1C=C[C@H]2[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3C)[C@H]1O5

nearest known ligand 0.82

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 14/20 0.82
OPRM1 P35372 14/20 0.82
OPRK1 P41145 13/20 0.82
MRGPRX2 Q96LB1 2/20 0.71
SLC22A1 O15245 1/20 0.71
ADRA2A P08913 1/20 0.71
ARRB1 P49407 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17302927 1.00 OPRD1 (0.82) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL13998949 1.00 OPRD1 (0.82) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL29368031 1.00 OPRD1 (0.82) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL16922133 1.00 OPRD1 (0.82) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL154049 1.00 OPRD1 (0.82) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
Hydrochloric Acid SCHEMBL27754465 0.99 OPRD1 (0.81) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL29380241 0.94 OPRD1 (0.72) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL16810050 0.93 OPRM1 (0.82) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
SCHEMBL27832558 0.91 OPRD1 (0.67) OPRD1OPRM1OPRK1
Diacetylmorphine SCHEMBL2346177 0.90 OPRM1 (0.71) OPRD1OPRM1OPRK1MRGPRX2SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118393042-A Method for detecting drugs in domestic sewage 广州智达实验室科技有限公司 2024-07-26 CN claimed
CN-114324639-B Mixed-mode weak cation solid phase extraction material and preparation method and application thereof 浙江工业大学 2023-09-29 CN claimed
CN-115290803-A LC-MS/MS qualitative and quantitative analysis method for 9 drugs in hair 广州金域司法鉴定技术有限公司 2022-11-04 CN claimed
CN-114264732-A Method for detecting drugs in hair 广州金域司法鉴定技术有限公司 2022-04-01 CN claimed
CN-110208072-B Human hair rapid lysis solution for trace drug detection and application thereof 江苏苏博生物医学科技南京有限公司 2021-11-16 CN claimed
CN-113219102-A Method for measuring content of toxic substances and metabolites thereof in sewage 南开大学 2021-08-06 CN claimed
CN-112903852-A Method for detecting 10 drugs in hair 广州金域司法鉴定技术有限公司 2021-06-04 CN claimed
CN-112229918-A UPLC-MS/MS method for determining distribution of metabolites in heroin addicted rats and mice and application thereof 中山大学 2021-01-15 CN claimed
CN-111426768-A Analysis method for simultaneously determining 11 kinds of drugs and metabolites thereof in domestic sewage 司法鉴定科学研究院 2020-07-17 CN claimed
CN-108593828-A Blood plasma prepares the detection method of drug and toxic content in card 李水军 2018-09-28 CN claimed
CN-104965035-A Method for screening toxic substances in sample by using solid phase support liquid-liquid extraction-GC MS INST FORENSIC SCIENCE MINISTRY PUBLIC SECURITY PRC 2015-10-07 CN claimed
CN-101813675-B LC-MS/MS analysis method for detecting morphinane alkaloid in whole blood and urine CRIMINAL INVEST DEPT OF SHANGHAI POLICE STATION 2012-11-14 CN claimed
CN-101923081-B Column switching LC-MS/MS analysis method for detecting morphine alkaloid in urine CRIMINAL INVEST BRIGADE OF SHANGHAI POLICE 2012-05-30 CN claimed
CN-101923081-A Column switching LC-MS/MS (Liquid Chromatography-Mass Spectrometry/Mass Spectrometry) analytical method for detecting morphine alkaloid in urine CRIMINAL INVEST BRIGADE OF SHANGHAI POLICE 2010-12-22 CN claimed
CN-101813675-A LC-MS/MS analysis method for detecting morphinane alkaloid in whole blood and urine CRIMINAL INVEST DEPT OF SHANGHAI POLICE STATION 2010-08-25 CN claimed
US-5843480-A Controlled release diamorphine formulation EURO-CELTIQUE, S.A. (LU) 1998-12-01 US claimed
CN-222825309-U Dry ice bath device for detecting drugs in domestic sewage 广东瀚正检测科技有限公司 2025-05-02 CN disclosed
CN-222812628-U Water sample collector for detecting common drugs in domestic sewage 广东瀚正检测科技有限公司 2025-04-29 CN disclosed
WO-2000078763-A2 NON-HYDROLYZABLE ANALOGS OF HEROIN METABOLITES SUITABLE FOR USE IN IMMUNOASSAY MICROGENICS CORPORATION (US) 2000-12-28 WO disclosed
WO-2000078763-A2 NON-HYDROLYZABLE ANALOGS OF HEROIN METABOLITES SUITABLE FOR USE IN IMMUNOASSAY MICROGENICS CORPORATION (US) 2000-12-28 WO disclosed