SCHEMBL7940075

SCHEMBL7940075

CC(C)(C)c1cccc(CCC(=O)N(CCO)C(C)(C)C)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA2 P00918 1/20 0.40
IAPP P10997 4/20 0.40
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
PYGL P06737 1/20 0.32
ALOX12 P18054 1/20 0.32
HSPA5 P11021 1/20 0.31
ALOX5 P09917 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943156 0.86 CA2 (0.41) HTTKMT2ACA2IAPPGABRA1
SCHEMBL7943048 0.84 IAPP (0.42) HTTKMT2AL3MBTL1CA2IAPP
SCHEMBL7940213 0.82 HSPA5 (0.50) HTTMEN1KMT2AL3MBTL1CA2
SCHEMBL7933780 0.81 IAPP (0.42) HTTMEN1KMT2AL3MBTL1CA2
SCHEMBL7940305 0.81 CYP2C19 (0.39) HTTMEN1KMT2AL3MBTL1SMN1; SMN2
SCHEMBL7942411 0.80 CA2 (0.40) HTTMEN1KMT2AL3MBTL1CA2
SCHEMBL7942438 0.79 IAPP (0.40) HTTMEN1KMT2AL3MBTL1CA2
SCHEMBL7943164 0.78 CA2 (0.41) HTTMEN1KMT2AL3MBTL1CA2
SCHEMBL7933599 0.77 ALDH1A1 (0.52) HTTMEN1KMT2AL3MBTL1ATM
SCHEMBL7944834 0.77 IAPP (0.40) HTTMEN1KMT2AL3MBTL1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-6075159-A USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-13 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed