Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179071 | 1.00 | NLRP3 (0.47) | NLRP3DGKALPAR1LPAR3PAM | |
| SCHEMBL13714813 | 0.99 | NLRP3 (0.45) | NLRP3DGKALPAR1LPAR3PAM | |
| SCHEMBL13996248 | 0.99 | NLRP3 (0.45) | NLRP3DGKALPAR1LPAR3PAM | |
| SCHEMBL12798523 | 0.94 | NLRP3 (0.40) | NLRP3DGKALPAR1LPAR3 | |
| SCHEMBL8614083 | 0.91 | EPHX2 (0.40) | NLRP3 | |
| SCHEMBL455925 | 0.88 | NLRP3 (0.43) | NLRP3MAPT | |
| SCHEMBL13863423 | 0.87 | EPHX2 (0.38) | NLRP3LPAR1LPAR3 | |
| SCHEMBL27210124 | 0.87 | LMNA (0.39) | NLRP3PAMTSHR | |
| SCHEMBL8614081 | 0.86 | LMNA (0.40) | NLRP3TSHR | |
| SCHEMBL13863434 | 0.83 | EPHX2 (0.35) | NLRP3DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228356-C | Norbornene polymerization catalyst system and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2005-11-23 | — | — | CN | disclosed |
| CN-1200017-C | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2005-05-04 | — | — | CN | disclosed |
| CN-1167720-C | Polymeric catalyst system of norbornaene and its preparing process | 中国科学院化学研究所 | 2004-09-22 | — | — | CN | disclosed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | disclosed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | disclosed |
| CN-1390867-A | Polymeric catalyst system of norbornaene and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-15 | — | — | CN | disclosed |
| CN-1388140-A | Nickel compound catalyst system for polymerization of norbornene and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | disclosed |
| CN-1388139-A | Norbornene polymerization catalyst system and its preparing process | CHINESE ACAD INST CHEMISTRY (CN) | 2003-01-01 | — | — | CN | disclosed |
| US-6262194-B1 | PREPARING HOMOPOLYMERS, COPOLYMERS OR BLOCK COPOLYMERS COMPRISING CYCLOOLEFINIC MONOMER UNITS, WHEREIN THE POLYMERIZATION IS CARRIED OUT IN PRESENCE OF METAL COMPLEX CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |