SCHEMBL7940135

SCHEMBL7940135

c1ccc2c(c1)CCN2CCN1CCc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
USP2 O75604 1/20 1.00
CDK4 P11802 1/20 1.00
ALOX15 P16050 1/20 1.00
CCND1 P24385 1/20 1.00
MAPT P10636 4/20 0.70
KDM4E B2RXH2 2/20 0.70
LMNA P02545 2/20 0.70
PTK2B Q14289 1/20 0.70
ESR2 Q92731 1/20 0.70
NPC1 O15118 2/20 0.69
RAB9A P51151 2/20 0.69
POLB P06746 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
TAAR1 Q96RJ0 1/20 0.51
TRPM5 Q9NZQ8 1/20 0.51
CHRM2 P08172 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30157536 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL30532191 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL29612232 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL3131059 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL7213519 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL25366135 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL1811216 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL3131072 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL14059746 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL4935582 0.88 ALDH1A1 (0.78) ALDH1A1MEN1KMT2AUSP2CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6262194-B1 PREPARING HOMOPOLYMERS, COPOLYMERS OR BLOCK COPOLYMERS COMPRISING CYCLOOLEFINIC MONOMER UNITS, WHEREIN THE POLYMERIZATION IS CARRIED OUT IN PRESENCE OF METAL COMPLEX CATALYST BASF AKTIENGESELLSCHAFT (DE) 2001-07-17 US disclosed
EP-0973813-A1 PRODUCTION OF HOMOCOPOLYMERS, CO-COPOLYMERS OR BLOCK COPOLYMERS FROM CYCLOOLEFINIC MONOMER UNITS BASF AKTIENGESELLSCHAFT (DE) 2000-01-26 EP disclosed
WO-1998045342-A1 PRODUCTION OF HOMOCOPOLYMERS, CO-COPOLYMERS OR BLOCK COPOLYMERS FROM CYCLOOLEFINIC MONOMER UNITS BASF AKTIENGESELLSCHAFT (DE) 1998-10-15 WO disclosed